The establishment of six years of Berry and Kang, from the beginning of the creation of a non-invasive prenatal genetic testing market in the East, in 2011, won the Grand Alliance capital A round of financing $17 million 800 thousand, in the middle of 2013, and received a $25 million B round of financing, led by Qiming venture investment. Subsequently, Berry held in 2014 to 2015 of non-invasive prenatal genetic testing commercial opportunity to become a leader after noninvasive prenatal genetic testing field of bgi. In 2016, Berry discovered the new progress is the backdoor landing A shares.

“Small company merger” or will become the precise medical mainstream business model

In May 31, 2016, the relevant media reports, the Irish biopharmaceutical company (JAZZ), pharmaceutical will be $1 billion 500 million acquisition of Celator pharmaceuticals (CPXX), the purchase price is about two times of Celator pharmaceutical market. Celator pharmaceutical stocks in 2016 is fully deserve star, after the company suspended March 14th announcement that the company’s drug VYXEOS by phase three clinical confirmed that acute myeloid leukemia (AML) in high-risk patients (grade two) overall survival rate increased significantly. The company shares resume trading day rose 400%, after continued to rise. As of May 31st closing price of $17.53. 3 months rose nearly 10 times already, led the NASDAQ market.

The medical merger has gradually become the main way for global capital exit. With the vigorous development of the medical field of entrepreneurial Israel as an example, startups grow to a certain extent, many choose to exit the merger case. Share investment investment investment investment enjoy Introduction Manager Wu Han, 2005 to 2014, a total of 62 Israeli medical health industry company mergers and acquisitions, the average operation time of medical and health industry companies for 12.3 years, from the first financing to exit the merger took an average of 8.68 years. However, this is mainly because the bio pharmaceutical and biotechnology and other segments of elongated capital return period, ordinary medical enterprises to invest in a relatively short period.

In the China capital market, mergers and acquisitions of listed companies into the precise medical case already exists, mergers and acquisitions also increased the story space for listed companies. In October 2015, a new day constant announcement, to 1 billion 566 million yuan acquisition boyalife 80% shares, boyalife became a subsidiary, constant new day in November 23, 2015, the resolution adopted by the general meeting of shareholders, a new day constant to take into the field of biology and medicine.

In May 11, 2015, the number of new announcement that the company intends to target specific non-public offering of shares to acquire three economic, medical and biological Oh Seoul crystal bio 100% stake, and to 13.20 yuan / share to 3 specific object given by 13 million 710 thousand shares to raise matching funds 154 million 600 thousand yuan for the underlying asset integration, capital arrangement. Xinkaiyuan also through this acquisition into the tumor early diagnosis, molecular diagnosis and gene sequencing of in vitro diagnostic services.

At the same time, the listed companies will choose to set up the way of mergers and acquisitions fund cut precision medical, choose investment targets in the global scope. In February 2016, the medical Dunlop announcement that intends to use the self financing of $95 million with the Yantai people and De Yuan equity investment management center (limited partnership) jointly set up a total size of not more than $100 million in global precision medical innovation investment fund. At present, the fund has invested in the field of liquid biopsy, the American Quanterix company, invested $11 million in the D round of financing way to increase its stake of 5.35%.

Will the possible acquisition of startups between

“European Rubber Journal” (ERJ) released the latest “2011 Annual Global Rubber Machinery report” shows that in 2011 the global rubber machinery sales increased 16%, reached a record $3 billion 863 million, including non tire tire equipment and equipment is 3: 1, non tire equipment sales growth faster than the tire equipment. This ranking shows that Chinese enterprises rising strength, European and American companies in trouble. Expect the global rubber machinery experienced in 2010 and 2011 after the rapid development will enter the stage of steady development, demand will maintain the level before the financial crisis in the middle of 2008.

China ranks second

This year is the calendar year to rank the greatest change in a year. The German H-F company (formerly Italy Krupp) with the acquisition and the Farrel wave at the top business. The leapfrog development of China mesnac, sales revenue increased 56% in second, this is the Chinese rubber machinery enterprises among the top three for the first time. Japan Kobe steel company sales revenue fell 5%, down to third. Holland VMI company for $262 million, ranked fourth. Japan’s MITSUBISHI heavy industry sales revenue increased 147%, ranked fifth, the largest increase. 95% growth in Dalian rubber sales revenue, ranked sixth, this is the first time into the top ten. Yiyang rubber machine, La Center Boro, Castro Esther and Guilin rubber machine in seventh, eighth, ninth and 10.

A new list of 5 companies, respectively, Germany Arburg company, Holland company, China groznyi SCUT bestry company and Sichuan Yaxi company and Dalian integrity of the company. In rubber machinery enterprise 30 strong, 14 China, Germany 7, Japan 3, Holland 2, Italy 1, France 1, Austria 1, India 1. Rubber machinery sales revenue of over $300 million enterprises from 1 in 2010 to 3, 2 and 200 million ~3 billion dollars, 3 100 million ~2 billion dollars, that big companies rubber machinery industry by the beginning of 2007 continues, and there are signs of accelerating.

The top ten in Kobe steel sales decreased slightly in other maintained a substantial growth, the growth rate in more than 50% of the MITSUBISHI heavy industries, Dalian rubber and mesnac. The top ten sales accounted for 54.1% of the total world rubber machinery, growth of 4 percentage points compared to 2010.

In the global rubber machinery in the top 30, Chinese enterprises accounted for 14 seats, occupy 4 seats in the top 10. Chinese enterprise concentration increased significantly and the top 3 market share from 26.5% last year rose to 33.5% before the rubber machine, the top 10 market share from 55.3% last year rose to 59.8%, indicating China rubber machinery companies obviously.

The market pattern has changed

Record sales revenue in 2011 most of the rubber machine company, full load production, delayed delivery orders and refused to have occurred. On the point of the area, a strong rebound in the Japanese market, Chinese market continued growth momentum, and market performance.

ERJ pointed out that in recent years the Japanese rubber machinery market share has been declining, 2010 dropped to 3% of the world’s lowest point, but in 2011 the Japanese rubber machinery market sales rebounded, growth of 135%, accounted for 5.7% of the global share. The sustainable development of China market, sales revenue growth of 36%, in the global market share increased to 31%. In recent years, some large projects in Southeast Asia near the end, demand for rubber machinery decreased slightly. In addition, some European big rubber processing projects stalled, leading to the relative difficulty of some European rubber machinery enterprises. The United States in 2011 without a rubber machinery enterprises to enter the top 30.

In terms of products, mechanical equipment market growth is higher than that of non tire rubber tire equipment growth, especially the conveyor belt and hose industry, the investment rate has been higher than that of the tire industry, strong demand for non tire equipment.

In addition, changes of rubber mixing equipment supply pattern of relative two years ago. Before the Asian countries such as Japan and South Korea from Kobe to buy steel smelting equipment, Europe, North America, India and other countries, and the purchase of H-F Farrel wave Mini mixer equipment. After the acquisition of H-F wave and Farrel Meaney, customers can choose in Kobe steel company and H-F. Tire customers because of concerns about mixing equipment procurement monopoly, often invite H-F and Kobe steel on bidding. Kobe steel company revealed that at least 2~3 European companies began to purchase the mixing equipment. H-F after the completion of the acquisition has also made rapid development, technical level of equipment and more on the steps, before the purchase of the product price is increased, the market for further expansion, the mixing equipment with annual sales of 150 million euros.

Promote the upgrading of the crisis

Generally think rubber machinery manufacturing enterprises, the financial crisis has brought great changes to the industry, most of which are positive. First of all, to meet customer needs and save money, more suppliers of rubber machine to shift production to lower labor cost countries, the production of more low-cost equipment.

Secondly, compared with the western countries rubber machinery manufacturing enterprises, Chinese rubber machinery enterprise and Japan now have more opportunities to contact with customers, more easily in the process, material and design to meet the needs of customers. According to ERJ observation, now rubber machinery manufacturing enterprises pay more attention to bring more value to customers. Different customers on the same equipment capacity, reliability, quality and adaptability have different requirements. This prompted the rubber machine manufacturing enterprises for various conditions to find the best solution to achieve the purpose of complete order delivery at low cost.

Once again, the world’s top tire enterprises now attach great importance to the construction of the green plant, to meet European standards, in order to bring from the automobile industry customers left a good impression. Chinese companies are slowly through these changes. Export oriented tire enterprises has already committed to producing higher quality, better performance of tire. Chinese tire enterprises purchase cheap local manufacturing rubber machine time is over.

A questionnaire survey for ERJ sales situation, in the investigation, planning for the future, more and more enterprises focus on product upgrading and modernization, expand production capacity ratio fell from 46% last year to 36%, product upgrading and modernization increased from 35% to 32% last year.

research firm Marketsand Markets recently released a new research report pointed out that with the global increase in demand for medical facilities, medical facilities and people on the spread of infection risk awareness, medical coatings market demand growth trend. Data show that the global medical coatings market size will reach $15 billion 150 million by 2021, a CAGR of 7.04%.

General medical coating Into two types: hydrophilic and hydrophobic coating paint. According to the requirements of medical facility, two kinds of coating can be used alone, also can be used. Hydrophilic coatings are widely used in all kinds of medical equipment such as catheter and introducer sheath, which has lower friction coefficient, excellent lubricity and durability etc..

Main application: coating including medical plastic surgery devices, cardiovascular medical equipment, optical equipment, endoscope, medical radiation equipment. At present, has developed a variety of new coatings, friction, can make the medical facilities reduce tissue and the new coating has excellent coating properties, wettability, adhesion, abrasion resistance and smoothness etc..

The study pointed out that North America is the world’s largest medical coatings market, and will continue until 2021. European medical coatings market growth rate is slightly higher than that of North America and the Asia Pacific region, the growth rate will be the highest, but its market share is still lower than that of North America and europe. The main manufacture of the United States, Germany, Japan, China as a global medical products, is the main consumer of medical materials, and China and India will be the main force to promote the development of the global medical coatings market.

M & a longmang completed, optimistic about the long-term development prospects

The company started in October and completed the acquisition of longmang, scale, total production capacity will reach 560 thousand tons, accounting for 20% in the domestic production, exports accounted for 42%, in the absolute leading position; to become the world’s fourth largest titanium dioxide enterprises after DuPont, Huntsman, Koster at the international level, the international competitiveness significantly enhanced.

Through the powerful combination of both sides, will be able to share the experience in product research and development achievements, longmang in the production of high quality product experience is helpful to realize the rapid promotion of company products.

In November 24th, Shandong Huifeng Petrochemical propane price rose 30, the implementation of 3900 yuan / ton, the normal operation of equipment manufacturers, the normal inventory.

Shandong Changyi Petrochemical propane price rose 30, the implementation of 3803 yuan / ton, the normal operation of equipment manufacturers.

In November 25th, Dongying Hualian Chemical propane price stability, the implementation of 3670 yuan / ton, factory shipments in general. Shandong Changyi Petrochemical propane price fell 60, the implementation of 3743 yuan / ton, the normal operation of equipment manufacturers. Shandong Huifeng Petrochemical propane price stability, the implementation of 3900 yuan / ton, the normal operation of equipment manufacturers, the normal inventory.

As time is cold, liquefied gas market demand of domestic stability, especially the downstream repair needs well, so as to support the liquefied gas market, the market price of 3793 yuan / ton, the propane Market support.

Recently, the domestic market price of propane have been high, the downstream demand gradually improved, in addition, the domestic refinery production is relatively small, the current low price of shipping resources worry free, high or slightly minor resources. According to the relevant data show that compared with the outbreak of the October, in November the price rise or slowed down, overall, the market is still optimistic about the scene of propane, bullish expectations may still be.

Hebei Nanpu saltern Co., bromine factory price 23500 yuan / ton, the annual production capacity of 4000 tons.

Shouguang area bromine plant operating normally, the local market temporarily stabilized, ex factory price of 23500 yuan / ton.

Yingkou Zhongchen Chemical Co., bromine device operating normally, ex factory price 23500 yuan / ton, the actual transaction price and other consulting, smooth shipment.

Bromine plant of Changyi saltworks Co Ltd started to normal range, factory price 23500 yuan / ton.

Bromine unit of Cangzhou Salt Group Corporation started low, the factory price of 23000 yuan / ton, inventory is not much, smooth shipment.

finance at present, the market in the short term performance of tight supply of bromine, plus the G20 summit ended, bromine production has a certain effect, the downstream market demand changed little, the decline is the current market supply of bromine supporting the market price of the main factors, the recent market dominated by consolidation.

In September 9th, the domestic parts of bromine market overview:

Haihua bromine plant operating normally, factory price temporarily stabilized at 24000 yuan / ton, the actual turnover of another discussion.

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